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A Shared Susceptibility Locus in the p53 Gene for both Gastric and Esophageal Cancers in a Northwestern Chinese Population
Genetic Testing and Molecular Biomarkers ( IF 1.1 ) Pub Date : 2020-12-16 , DOI: 10.1089/gtmb.2020.0192
Juan Cao 1 , Zhiqiang Chen 2 , Chaoyong Tian 3 , Jia Yu 4 , Hongfei Zhang 4 , Jingwen Yang 4 , Wenjun Yang 4
Affiliation  

Background: Upper gastrointestinal tract cancers are the leading causes of cancer-related deaths in Northwest China and they share many similarities in terms of histological type, risk factors, and genetic variants. We hypothesized that shared common single-nucleotide polymorphisms (SNPs) in the p53 pathway exist between patients with gastric and esophageal cancer (EC) patients.
更新日期:2020-12-22
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