Background and Aims: Serotonin syndrome (SS) is a highly underdiagnosed drug-induced clinical syndrome. Under diagnosis is partly due to the unawareness of this syndrome by physicians. The aim of this study is to assess the knowledge, attitude and practice of SS among neuro physicians in India. Methods: A cross-sectional survey using a self-administered questionnaire was carried out among neuro physicians in India. Neuro physicians attending the various neurological conferences and meetings were approached to participate in the study. Result: A total of 150 neuro physicians responded to the survey. About 31% of participants correctly recognized the criteria for SS. Only 17% of the neuro physicians considered clonus as the most important feature in SS. Very few physicians correctly identified serotonergic agents causing serotonin syndrome. Similarly, a very low percentage of neuro physicians correctly identified the drugs used in the management of SS. Drugs used for the treatment of SS were incorrectly recognized as drugs causing SS. Clonus is the most specific feature for SS. However, examination for clonus is not a routine phenomenon in clinical practice among neuro physicians. Conclusion: This study shows great deficiencies in all domains of SS among neuro physicians. There is a need to make every doctor aware of SS by educational programs.


中文翻译：

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神经内科医生对血清素综合征的知识、态度和实践 (KAP) 研究


背景和目的： 5-羟色胺综合征（SS）是一种高度诊断不足的药物诱导的临床综合征。诊断不足的部分原因是医生没有意识到这种综合征。本研究的目的是评估印度神经内科医生对 SS 的知识、态度和实践。方法：在印度的神经内科医生中使用自填式问卷 进行横断面调查。参加了各种神经学会议的神经内科医生被联系参加了这项研究。结果：一个 共有 150 名神经内科医生对调查做出了回应。大约 31% 的参与者正确识别了 SS 的标准。只有 17% 的神经内科医生认为阵挛是 SS 最重要的特征。很少有医生能正确识别导致血清素综合征的血清素能药物。同样，非常低比例的神经内科医生正确识别了用于治疗 SS 的药物。用于治疗 SS 的药物被错误地识别为引起 SS 的药物。Clonus 是 SS 最具体的功能。然而，在神经内科医生的临床实践中，检查阵挛并不是一种常规现象。结论：本研究显示神经内科医生在 SS 的所有领域都存在很大缺陷。有必要通过教育计划让每位医生了解 SS。