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Cardiopulmonary Impact of Particulate Air Pollution in High-Risk Populations
Journal of the American College of Cardiology ( IF 21.7 ) Pub Date : 2020-12-01 , DOI: 10.1016/j.jacc.2020.10.020
Jonathan D Newman 1 , Deepak L Bhatt 2 , Sanjay Rajagopalan 3 , John R Balmes 4 , Michael Brauer 5 , Patrick N Breysse 6 , Alison G M Brown 7 , Mercedes R Carnethon 8 , Wayne E Cascio 9 , Gwen W Collman 10 , Lawrence J Fine 7 , Nadia N Hansel 11 , Adrian Hernandez 12 , Judith S Hochman 13 , Michael Jerrett 14 , Bonnie R Joubert 15 , Joel D Kaufman 16 , Ali O Malik 17 , George A Mensah 18 , David E Newby 19 , Jennifer L Peel 20 , Jeffrey Siegel 21 , David Siscovick 22 , Betsy L Thompson 23 , Junfeng Zhang 24 , Robert D Brook 25
Affiliation  

Fine particulate air pollution <2.5 μm in diameter (PM2.5) is a major environmental threat to global public health. Multiple national and international medical and governmental organizations have recognized PM2.5 as a risk factor for cardiopulmonary diseases. A growing body of evidence indicates that several personal-level approaches that reduce exposures to PM2.5 can lead to improvements in health endpoints. Novel and forward-thinking strategies including randomized clinical trials are important to validate key aspects (e.g., feasibility, efficacy, health benefits, risks, burden, costs) of the various protective interventions, in particular among real-world susceptible and vulnerable populations. This paper summarizes the discussions and conclusions from an expert workshop, Reducing the Cardiopulmonary Impact of Particulate Matter Air Pollution in High Risk Populations, held on May 29 to 30, 2019, and convened by the National Institutes of Health, the U.S. Environmental Protection Agency, and the U.S. Centers for Disease Control and Prevention.

中文翻译:


空气颗粒物污染对高危人群心肺的影响



直径<2.5微米的细颗粒空气污染(PM2.5)是对全球公共卫生的主要环境威胁。多个国家和国际医学和政府组织已将 PM2.5 视为心肺疾病的危险因素。越来越多的证据表明,几种减少 PM2.5 暴露的个人方法可以改善健康终点。包括随机临床试验在内的新颖且具有前瞻性的策略对于验证各种保护性干预措施的关键方面(例如可行性、功效、健康益处、风险、负担、成本)非常重要,特别是在现实世界的易感人群和弱势人群中。本文总结了 2019 年 5 月 29 日至 30 日由美国国立卫生研究院、美国环境保护署、和美国疾病控制与预防中心。
更新日期:2020-12-01
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