In this study; an easy, practical, and selective sensor has been developed for the electrochemical determination of riboflavin. To prepare the modified electrode, the gold nanoparticle was deposited on the pencil graphite electrode (AuNP/PGE) by the method of chronoamperometry at −3.0 V for 30 s in 0.5 M H₂SO₄ solution containing 10 mM tetrachloroaurate. Functionalized multi-walled carbon nanotube (f-MWCNT) solution was dropped on prepared AuNP/PGE and the functionalized multi-walled carbon nanotube/gold nanoparticle/pencil graphite electrode (f-MWCNT/AuNP/PGE) was prepared for measurements. Characterization studies of the prepared sensor were performed using cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), energy-dispersive X-ray spectroscopy (EDX), and X-ray photoelectron spectroscopy (XPS) methods. The surface morphology of the prepared sensor was investigated by field emission scanning electron microscopy (FESEM). Differential pulse voltammetry (DPV) was used to carry out electrochemical measurements in phosphate buffer solution pH 4.0. Limit of detection (LOD) and limit of quantitation (LOQ) values were found to be 0.0352 and 0.118 μmol l⁻¹, respectively. The fabricated sensor showed excellent anti-interference ability against ascorbic acid (AA) and glucose (G). The applicability of the constructed sensor to real samples was investigated and good recovery values were achieved. As a result, it has been seen that the modified electrode is applicable in applications of riboflavin determination.

在这项研究中; 已经开发了一种简单、实用和选择性的传感器，用于核黄素的电化学测定。为了制备修饰电极，通过计时电流法在 0.5 MH ₂ SO _{4 中}在 -3.0 V 下沉积 30 秒，将金纳米颗粒沉积在铅笔石墨电极 (AuNP/PGE) 上含有 10 mM 四氯金酸盐的溶液。将功能化多壁碳纳米管 (f-MWCNT) 溶液滴在制备的 AuNP/PGE 上，制备功能化多壁碳纳米管/金纳米颗粒/铅笔石墨电极 (f-MWCNT/AuNP/PGE) 进行测量。使用循环伏安法 (CV)、电化学阻抗谱 (EIS)、能量色散 X 射线光谱 (EDX) 和 X 射线光电子能谱 (XPS) 方法对制备的传感器进行表征研究。通过场发射扫描电子显微镜（FESEM）研究制备的传感器的表面形貌。差分脉冲伏安法 (DPV) 用于在 pH 4.0 的磷酸盐缓冲溶液中进行电化学测量。发现检测限 (LOD) 和定量限 (LOQ) 值为 0。分别为μ mol l ^-1。制造的传感器对抗坏血酸（AA）和葡萄糖（G）显示出优异的抗干扰能力。研究了构建的传感器对实际样品的适用性，并获得了良好的回收率值。结果表明，修饰电极适用于核黄素测定的应用。