Piperonal, an important aromatic aldehyde containing the benzene ring fused to 1, 3- dioxolane moiety, widely occurred in nature and known for its fragrance similar to vanillin and cherry. Alterations in its structural features led to the access of a wide range of piperonal derivatives viz. pyrazolines, chalcones, benzothiazepines, benzoxazoles, triazoles etc. having remarkable pharmacological properties like antimicrobial, anticancer, antidiabetic, antitubercular activities, etc. Therefore, the present study has been designed to highlight the progress made in the area of piperonal and its derivatives till date with respect to their synthesis and pharmacological activities. This may facilitate the synthesis of more novel derivatives with improved biological activities. Various search engines like google, Pubmed, Scopus etc. were used to gather the related information using different keywords.

胡椒醛是一种重要的芳香醛，它含有与1，3-二氧戊环部分稠合的苯环，在自然界广泛存在，并以类似于香兰素和樱桃的香气而闻名。其结构特征的改变导致获得了广泛的胡椒衍生物。吡唑啉，查耳酮，苯并硫氮杂卓，苯并恶唑，三唑等具有显着的药理特性，如抗微生物，抗癌，抗糖尿病，抗结核活性等。因此，本研究旨在强调迄今为止在胡椒及其衍生物领域中的进展。关于它们的合成和药理活性。这可以促进具有改善的生物活性的更多新型衍生物的合成。各种搜索引擎，例如Google，Pubmed，Scopus等。