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M2‐like tumor‐associated macrophages‐secreted Wnt1 and Wnt3a promotes dedifferentiation and metastasis via activating β‐catenin pathway in thyroid cancer
Molecular Carcinogenesis ( IF 3.0 ) Pub Date : 2020-12-07 , DOI: 10.1002/mc.23268
Juan Lv 1 , Zhi-Ping Feng 1 , Fu-Kun Chen 1 , Chao Liu 1 , Li Jia 1 , Peng-Jie Liu 1 , Chuan-Zhou Yang 1 , Fei Hou 1 , Zhi-Yong Deng 1
Affiliation  

Thyroid carcinoma (TC) has been a global issue for its rapid increasing incidence worldwide. Although most TC was not so aggressive with a good prognosis, treatment against anaplastic TC was relatively limited and the mechanisms are not well elucidated yet.

中文翻译:


M2样肿瘤相关巨噬细胞分泌的Wnt1和Wnt3a通过激活β-连环蛋白途径促进甲状腺癌的去分化和转移



甲状腺癌(TC)因其在全球范围内的发病率迅速增加而成为一个全球性问题。尽管大多数TC的侵袭性不那么好,预后良好,但针对间变性TC的治疗相对有限,且其机制尚未得到很好的阐明。
更新日期:2020-12-14
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