Rational Design of Ratiometric Luminescence Thermometry Based on Thermally Coupled Levels for Bioapplications,Laser & Photonics Reviews

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Rational Design of Ratiometric Luminescence Thermometry Based on Thermally Coupled Levels for Bioapplications
Laser & Photonics Reviews ( IF 9.8 ) Pub Date : 2020-12-06 , DOI: 10.1002/lpor.202000319
Hao Suo _{1,

2} , Xiaoqi Zhao ₁ , Zhiyu Zhang ₁ , Yu Wang ₂ , Jiashu Sun ₁ , Minkun Jin ₁ , Chongfeng Guo ₁

Affiliation

Noninvasive lanthanide‐doped optical thermometers based on fluorescent intensity ratio (FIR) technique have emerged as promising noncontact tools for detecting the inaccessible objects at different scales. Currently, the theoretical and experimental investigations of various influential factors on thermal performances of luminescence thermometers have become one of the hotspots to develop highly sensitive optical thermometers. On the other hand, near‐infrared (NIR) light‐responsive nanothermometers with deep‐tissue penetration have been widely applied for subcutaneous and intracellular thermometry, which could be integrated with optical heating and imaging functions to construct all‐in‐one thermometer‐heater platforms for cancer diagnosis and therapy. In this review, the recent advances in luminescence thermometry based on the thermally coupled levels (TCLs) are elaborately introduced from fundamental aspects to possible biomedical applications, with the perspective and outlook in the emerging challenges of FIR thermometers applied in biomedical science.

中文翻译：

基于热耦合能级的比例发光法在生物应用中的合理设计

基于荧光强度比（FIR）技术的无创掺杂镧系元素光学温度计已成为有前途的非接触式工具，可用于检测不同规模的不可访问物体。目前，对发光温度计热性能的各种影响因素的理论和实验研究已成为开发高灵敏度光学温度计的热点之一。另一方面，具有深层组织穿透力的近红外（NIR）光响应纳米温度计已被广泛用于皮下和细胞内测温，可以与光学加热和成像功能集成在一起以构建多功能一体式温度计加热器癌症诊断和治疗平台。在这篇评论中

更新日期：2021-01-08

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