当前位置: X-MOL 学术BioEssays › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Network architecture and sex chromosome turnovers
BioEssays ( IF 3.2 ) Pub Date : 2020-12-07 , DOI: 10.1002/bies.202000161
Wenjing Tao 1 , Matthew A Conte 2 , Deshou Wang 1 , Thomas D Kocher 2
Affiliation  

Recent studies have revealed an astonishing diversity of sex chromosomes in many vertebrate lineages, prompting questions about the mechanisms of sex chromosome turnover. While there is considerable population genetic theory about the evolutionary forces promoting sex chromosome replacement, this theory has not yet been integrated with our understanding of the molecular and developmental genetics of sex determination. Here, we review recent data to examine four questions about how the structure of gene networks influences the evolution of sex determination. We argue that patterns of epistasis, arising from the structure of genetic networks, may play an important role in regulating the rates and patterns of sex chromosome replacement.

中文翻译:

网络架构和性染色体周转

最近的研究揭示了许多脊椎动物谱系中性染色体的惊人多样性,引发了有关性染色体更新机制的问题。虽然关于促进性染色体替换的进化力量有相当多的群体遗传理论,但该理论尚未与我们对性别决定的分子和发育遗传学的理解相结合。在这里,我们回顾了最近的数据,以研究关于基因网络结构如何影响性别决定进化的四个问题。我们认为,由遗传网络结构产生的上位性模式可能在调节性染色体替换的速率和模式方面发挥重要作用。
更新日期:2020-12-07
down
wechat
bug