VQ proteins are a class of plant-specific proteins containing the conserved motif FxxhVQxhTG（h denotes hydrophobic residues and x represents any amino acid）and are named VQ for the V and Q residues. By analyzing the structure of VQ members it was found that most VQ genes do not contain introns and the number of encoded amino acids is less than 300 aa. A majority of VQ proteins are located in the nucleus. Accumulated evidence has highlighted the importance of VQ proteins mainly participating in signal pathways through interacting with partners (eg. WRKYs and MAPKs) to regulate plant growth and development and respond to biotic and abiotic stresses. This review primarily focuses on the structure of VQ members in plant kingdom and the biological function and the mechanism of VQ protein action, and discusses recent advances in understanding the pivotal role of VQ-motif, which provides a solid foundation for further exploration on VQ proteins.

VQ蛋白是一类植物特异性蛋白，包含保守的FxxhVQxhTG基序（h表示疏水性残基，x表示任何氨基酸），并分别称为VQ和Q残基。通过分析VQ成员的结构，发现大多数VQ基因不包含内含子，编码的氨基酸数少于300个氨基酸。大多数VQ蛋白位于细胞核中。积累的证据凸显了VQ蛋白主要通过与伴侣（例如WRKY和MAPK）相互作用来参与信号途径，以调节植物生长和发育并对生物和非生物胁迫做出反应的重要性。这篇综述主要关注植物界中VQ成员的结构以及VQ蛋白作用的生物学功能和机制，