OBJECTIVE To estimate the frequency of spontaneous hemoperitoneum in pregnancy (SHiP) in women with endometriosis achieving pregnancy with in vitro fertilization (IVF). DESIGN Retrospective case series. SETTING Referral academic assisted reproductive technology (ART) center. PATIENT(S) Three hundred and forty-eight women with a history of surgery for endometriosis and women with ovarian endometriomas or deep endometriotic nodules detected at basal transvaginal ultrasound performed before IVF cycle. INTERVENTION(S) Information obtained from patients' charts on basal characteristics, IVF cycle, and pregnancy outcomes, and binomial distribution model created to determine the 95% confidence interval (CI) of the proportion of SHiP. MAIN OUTCOME MEASURE(S) Rate of SHiP. RESULT(S) Overall, 362 pregnancies were included, among which 238 (66%) had a history of previous surgery for endometriosis and 231 (64%) had endometriosis detected at ultrasound (107 women, 30%, had both). Pregnancies were achieved after fresh and frozen cycles in 244 (67%) and 118 (33%) women, respectively. One case of SHiP was recorded, corresponding to a rate of 0.3%. CONCLUSION(S) In the general population of women with endometriosis undergoing IVF, SHiP is uncommon. Future studies should better identify the risk factors for SHiP to disentangle the subgroups of women at higher risk.

中文翻译：

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妊娠期子宫内膜异位症和自发性腹腔积血：评估通过体外受精怀孕的妇女的风险程度

目的 估计体外受精（IVF）妊娠子宫内膜异位症女性妊娠期自发性腹腔积血（SHIP）的发生率。设计回顾性案例系列。设置 转介学术辅助生殖技术 (ART) 中心。患者 348 名有子宫内膜异位症手术史的女性和有卵巢子宫内膜异位症或深部子宫内膜异位结节的女性，在 IVF 周期前进行的基础经阴道超声检测到。干预 从患者图表中获得的关于基础特征、IVF 周期和妊娠结果的信息，以及为确定 SHiP 比例的 95% 置信区间 (CI) 而创建的二项分布模型。主要结果指标 出货率。结果 总共包括 362 次怀孕，其中 238 人（66%）有子宫内膜异位症手术史，231 人（64%）超声检测到子宫内膜异位症（107 名女性，30%，两者都有）。分别有 244 名 (67%) 和 118 名 (33%) 女性在新鲜和冷冻周期后成功怀孕。记录了 1 例 SHiP，对应的比率为 0.3%。结论 (S) 在接受 IVF 的子宫内膜异位症女性的一般人群中，SHiP 并不常见。未来的研究应该更好地确定 SHiP 的风险因素，以解开高风险女性亚群。结论 (S) 在接受 IVF 的子宫内膜异位症女性的一般人群中，SHiP 并不常见。未来的研究应该更好地确定 SHiP 的风险因素，以解开高风险女性亚群。结论 (S) 在接受 IVF 的子宫内膜异位症女性的一般人群中，SHiP 并不常见。未来的研究应该更好地确定 SHiP 的风险因素，以解开高风险女性亚群。