Clinically, acute cerium dioxide poisoning or damage is very rare. Here, the investigator reported a case about the patient who accidental ingested cerium dioxide nanoparticles during work shift. The patient recovered well after the treatment with removal of cerium and restoring coagulation factor activity. The author also reviewed relative literatures to discuss the potential mechanism of coagulation disorders following cerium dioxide nanoparticles ingestion. This case is the first report in the world about acute oral poisoning due to cerium dioxide nanoparticles, with the exact exposure concentration.

中文翻译：

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意外摄入二氧化铈纳米颗粒后的凝血障碍

临床上，急性二氧化铈中毒或损害非常罕见。在这里，研究人员报告了一起患者在轮班期间意外摄入二氧化铈纳米颗粒的情况。治疗后患者康复良好，去除了铈并恢复了凝血因子的活性。作者还回顾了相关文献，以讨论二氧化铈纳米粒子摄入后凝血功能异常的潜在机制。该病例是世界上第一个关于二氧化铈纳米粒子引起的急性口腔中毒的确切报道，其确切的暴露浓度。