While CDD directly to the CSF can provide a constant delivery of the dopaminergic drug resulting in a more stable treatment effect without the limitations of traditional oral therapy without peripheral effects, it is still young and longitudinal data is lacking. These experimental therapies show promise and further investigation into their efficacy and safety could extend the frontiers for management of PD.

中文翻译：

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帕金森病的鞘内和脑室内多巴胺

虽然 CDD 直接到 CSF 可以提供多巴胺能药物的持续递送，导致更稳定的治疗效果，而没有传统口服疗法的局限性，没有外周效应，但它仍然很年轻，缺乏纵向数据。这些实验性疗法显示出前景，对其有效性和安全性的进一步研究可以扩展 PD 管理的前沿。