The significance of periostin as a biomarker of Th2-induced airway inflammation has recently been highlighted in adult patients with allergic diseases. It may help identify drug-responsive inflammatory phenotypes, particularly in children. However, little is known about the usefulness of this parameter as a biomarker for allergic diseases in children. Furthermore, it is not known how much adolescent bone metabolism affects allergic inflammation.

中文翻译：

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青少年血清骨膜素水平。

最近，骨膜素作为 Th2 诱导的气道炎症生物标志物的重要性在患有过敏性疾病的成年患者中得到了强调。它可能有助于识别药物反应性炎症表型，特别是在儿童中。然而，人们对该参数作为儿童过敏性疾病生物标志物的有用性知之甚少。此外，尚不清楚青春期骨代谢对过敏性炎症的影响有多大。