Bacteria of the genus Streptomyces are used in multiple applications in the medical field owing to their ability to generate large quantities of secondary metabolites. Chromatographic purification of Streptomyces sp. MJM3055 led to the isolation of 1 new streptenol derivative, 1-O-acetylstreptenol A (2), along with (3E,8E)-1-hydroxydeca-3,8-dien-5-one (1), streptenol A (3), cyclo-(L-Ile-L-Pro) (4), streptazolin (5), and 7-O-acetylstreptazolin (6). The structures were elucidated by interpretation of combined mass spectrometry, circular dichroism, and 2-dimensional nuclear magnetic resonance spectroscopic data. Among these isolated compounds, compound 1 exhibited strong cytotoxic effects against Jurkat T cells.

链霉菌属细菌由于其产生大量次生代谢产物的能力而在医学领域中有多种应用。链霉菌的色谱纯化。MJM3055导致分离出一种新的链烯醇衍生物1- O-乙酰基链烯醇A（2），以及（3 E，8 E）-1-羟基癸3,8-dien-5-one（1），链烯醇A （3），环-（L-Ile-L-Pro）（4），链霉菌灵（5）和7- O-乙酰基链霉菌灵（6）。通过解释组合质谱，圆二色性和二维核磁共振光谱数据来阐明结构。在这些分离的化合物中，化合物1对Jurkat T细胞表现出强大的细胞毒性作用。