A general strategy for the synthesis of indolyl cyclobutanones via a tandem Brønsted acid catalyzed 2-hydroxycyclobutanone activation–indole nucleophilic addition has been exploited. The procedure leads to a wide range of 2- and 3-functionalized indole derivatives in good to high yields with broad substrate scope.

中文翻译：

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催化一锅合成吲哚基环丁酮

通过串联布朗斯台德酸催化的2-羟基环丁酮活化-吲哚亲核加成反应合成吲哚基环丁酮的一般策略已经被开发出来。该方法导致了范围广泛的2-和3-官能化的吲哚衍生物，具有良好的产率和高的收率，具有广泛的底物范围。