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Radiobiological effects of the interruption time with Monte Carlo Simulation on multiple fields in photon beams
Journal of Applied Clinical Medical Physics ( IF 2.0 ) Pub Date : 2020-12-03 , DOI: 10.1002/acm2.13110
Hisashi Nakano 1 , Daisuke Kawahara 2 , Satoshi Tanabe 1 , Satoru Utsunomiya 3 , Takeshi Takizawa 1, 4 , Madoka Sakai 1 , Hirotake Saito 1 , Atsushi Ohta 1 , Motoki Kaidu 5 , Hiroyuki Ishikawa 5
Affiliation  

The interruption time is the irradiation interruption that occurs at sites and operations such as the gantry, collimator, couch rotation, and patient setup within the field in radiotherapy. However, the radiobiological effect of prolonging the treatment time by the interruption time for tumor cells is little evaluated. We investigated the effect of the interruption time on the radiobiological effectiveness with photon beams based on a modified microdosimetric kinetic (mMK) model.

中文翻译:

蒙特卡洛模拟的中断时间对光子束中多个场的放射生物学影响

中断时间是发生在放射治疗现场和机架(如机架,准直仪,卧榻旋转和患者设置)中的照射中断。然而,很少评估通过中断肿瘤细胞延长治疗时间的放射生物学效果。我们基于改进的微剂量动力学(mMK)模型,研究了中断时间对光子束放射生物学有效性的影响。
更新日期:2020-12-28
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