In this review, we summarize and discuss the trends and supporting findings in scientific literature on the gut mucosa immune role in European sea bass (Dicentrarchus labrax L.). Overall, the purpose is to provide an updated overview of the gastrointestinal tract functional regionalization and defence barriers. A description of the available information regarding immune cells found in two immunologically-relevant intestinal compartments, namely epithelium and lamina propria, is provided. Attention has been also paid to mucosal immunoglobulins and to the latest research investigating gut microbiota and dietary manipulation impacts. Finally, we review oral vaccination strategies, as a safe method for sea bass vaccine delivery.

在这篇综述中，我们总结并讨论了有关欧洲鲈鱼中肠粘膜免疫作用的科学文献的趋势和支持性研究结果（Dicentrarchus labrax L.）。总体而言，其目的是提供胃肠道功能分区和防御障碍的最新概况。提供了有关在两个与免疫学相关的肠道区室（即上皮和固有层）中发现的免疫细胞的可用信息的描述。还已经注意粘膜免疫球蛋白和研究肠道菌群和饮食操作影响的最新研究。最后，我们回顾了口服疫苗接种策略，作为海鲈疫苗接种的安全方法。