Purpose

To determine factors associated with non-adherence to contact lens wear schedule involving single vision and myopia control contact lenses in children.

Methods

Data from 379 children enrolled in a prospective, double masked, randomized clinical trial, aged 8–13 years, cycloplegic spherical equivalent of -0.75 to -3.50D and wearing either: single vision silicone hydrogel (SiH) CL (control lens); two anti-myopia SiH CL that incorporated relative plus in the central and periphery in a stepped manner (test lens I and II); and two extended depth of focus hydrogel CL (test lens III and IV) was considered. A questionnaire was administered to the participants at every scheduled visit and gathered information on days of wear/week and subjective assessments of ocular comfort and visual quality on an analog scale of 1–10.Participants were categorized as “Adherent” when lens wear was ≥ 6 days/week or “Non-adherent” when lens wear ≤ 5 days/week. Categorized adherence data was summarized as a percentage across visits for each CL type. Differences between the two groups were analyzed using linear mixed model.

Results

For the control lens, 79.6 % participants were adherent as compared to 63.7%–74.6% with test lenses (p=0.026). Non-adherence was greater in those that discontinued (p<0.001). Subjective ratings of visual quality for static and dynamic tasks were lower with non-adherent wearers and more variable between visits. Ocular comfort was also poorer in non-adherent wearers irrespective of lens material or lens design. Male gender, lower baseline myopia, lower high contrast visual acuity and esophoria were associated with a higher risk of non-adherence.

Conclusions

The study identified a wide range of factors associated with non-adherence to lens wear schedule. Paying specific attention to these factors when evaluating patients for CL wear and taking steps to ensure satisfaction in lens wear may promote longer term continuation of wear.

中文翻译：

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探索不遵守隐形眼镜配戴时间表：佩戴单视和近视控制隐形眼镜的儿童的主观评估和患者相关因素

目的

确定与儿童单视和近视控制隐形眼镜不遵守隐形眼镜配戴时间表相关的因素。

方法

来自参加前瞻性、双盲、随机临床试验的 379 名儿童的数据，这些儿童的年龄为 8-13 岁，散瞳球镜等效值为 -0.75 至 -3.50D，并佩戴：单视硅水凝胶 (SiH) CL（对照镜片）；两个抗近视SiH CL，在中央和周边以阶梯方式结合相对加号（测试镜片I和II）；并考虑了两种扩展焦深水凝胶 CL（测试镜片 III 和 IV）。在每次预定访问时向参与者发放问卷，并收集有关佩戴天数/周的信息以及以 1-10 的模拟量表对眼睛舒适度和视觉质量的主观评估。当镜片佩戴≥当镜片佩戴 ≤ 5 天/周时，6 天/周或“非依从性”。分类的依从性数据总结为每种 CL 类型的访问百分比。使用线性混合模型分析两组之间的差异。

结果

对于对照镜片，79.6% 的参与者依从性，而使用测试镜片的参与者为 63.7%–74.6% (p=0.026)。停药者的不依从性更高（p<0.001）。非依从佩戴者对静态和动态任务的视觉质量主观评价较低，并且在两次访问之间变化较大。无论镜片材料或镜片设计如何，非依从佩戴者的眼睛舒适度也较差。男性、较低的基线近视、较低的高对比度视力和食管与较高的不依从性风险相关。

结论

该研究确定了与不遵守镜片佩戴时间表相关的广泛因素。在评估患者的 CL 佩戴情况并采取措施确保镜片佩戴满意度时特别注意这些因素可能会促进长期佩戴。