A concise synthesis of an amide-functionalized [7]helicene-like molecule was achieved via the intramolecular amidation of an in-situ-generated biaryl δ-amino acid derivative. An X-ray analysis of racemic mixture of this helicene-like molecule revealed a helically twisted π-system and that the (M)- and (P)-isomers associate pairwise via hydrogen-bonding interactions, which results in a one-dimensional columnar packing in the crystal structure.

中文翻译：

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通过分子内酰胺化反应合成酰胺功能化的[7] Hel烯类分子

的简明合成酰胺官能化的[7]螺烯样分子经由的分子内酰胺化实现中-原位-生成二芳基δ氨基酸衍生物。X射线分析该螺旋状分子的外消旋混合物显示出螺旋扭曲的π系统，并且（M ）和（P ）异构体通过氢键相互作用成对缔合，形成一维圆柱状堆积在晶体结构中。