National Key Laboratory of Science and Technology on Advanced Composites in Special Environments Center for Composite Materials and Structures Harbin Institute of Technology Harbin 150080 P. R. China
School of Electronics and Information Engineering Harbin Institute of Technology Harbin 150080 P. R. China
Key Laboratory of Functional Inorganic Material Chemistry (Ministry of Education), School of Chemistry and Materials Science Heilongjiang University Harbin 150001 P. R. China
School of Aerospace Mechanical and Mechatronic Engineering The University of Sydney Sydney NSW 2006 Australia
Shenzhen STRONG Advanced Materials Research Institute Co., Ltd. Shenzhen 518035 P. R. China
In article number 2000067 Lin Yang and co‐workers find that the hydrophobic interaction between the SARS‐CoV‐2 spike protein and the ACE2 protein is significantly greater than that between the SARS‐CoV spike protein and the ACE2 protein. At the docking site, the hydrophobic portions of the hydrophilic side chains of SARS‐CoV‐2 S are found to be involved in the hydrophobic interaction between the SARS‐CoV‐2 spike protein and ACE2.
Lin Yang和同事在文章编号2000067中发现，SARS-CoV-2刺突蛋白与ACE2蛋白之间的疏水相互作用显着大于SARS-CoV刺突蛋白与ACE2蛋白之间的疏水相互作用。在对接位点，SARS-CoV-2 S亲水性侧链的疏水部分被发现与SARS-CoV-2尖峰蛋白和ACE2之间的疏水相互作用有关。
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