Introduction

Few studies have investigated the performance of screening tools in truly sarcopenic individuals, especially subgroups of this population, or in comparison to previous and current criteria for the definition of sarcopenia.

Objectives

Evaluate the performance of SARC-F and SARC-CalF in screening for sarcopenia in patients with Parkinson's disease (PD) in comparison to the diagnostic criteria proposed by the 2010 (1) and 2019 (2) European Working Group on Sarcopenia in Older People (EWGSOP).

Methods

A methodological, cross-sectional study was conducted involving male and female patients ≥60 years of age diagnosed with PD in outpatient care. The risk of sarcopenia was assessed using the SARC-F and SARC-CalF questionnaires, the latter of which includes the calf circumference as an additional item.

Results

Sixty patients were evaluated (mean age: 68.9 ± 6.5 years). The prevalence of sarcopenia was 21.7% according to EWGSOP-2 and 55.0% according to EWGSOP-1. Positive screening for sarcopenia was 30% according to the SARC-F and 36.7% according to SARC-CalF. The sensitivity of the SARC-F for the detection of sarcopenia was 27.2% and 23.1% using the criteria of the 2010 and 2019 consensuses, respectively. The comparative analysis of the SARC-CalF revealed a better performance in the diagnostic discrimination with the addition of calf circumference, with sensitivity ranging from 53.8 to 54.5%. Higher sensitivity was found on items addressing the ability to stand up from a chair and climb stairs (69.2%) and the occurrence of falls (76.9%) compared to the use of the complete questionnaire.

Conclusion

Relatively low sensitivity and an underestimation of sarcopenia were found in the analysis of the SARC-F as a screening tool for sarcopenia. Thus, a significant number of sarcopenic patients would not be identified using this screening tool alone. The SARC-CalF performed better than the SARC-F.

中文翻译：

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SARC-F和SARC-CalF在帕金森氏病老年人筛检肌肉减少症中的作用

介绍

很少有研究调查筛查工具在真正的肌肉减少症患者中的表现，尤其是该人群的亚组，或者与先前和当前的肌肉减少症定义标准进行比较。

目标

与2010年（1）和2019年（2）欧洲老年人肌肉减少症工作组提出的诊断标准相比，评估SARC-F和SARC-CalF在筛查帕金森氏病（PD）患者的肌肉减少症时的表现（ EWGSOP）。

方法

进行了一项方法学横断面研究，涉及在门诊治疗中被诊断为PD的≥60岁的男性和女性患者。使用SARC-F和SARC-CalF问卷评估了肌肉减少症的风险，后者包括小腿围作为附加项目。

结果

评估了60名患者（平均年龄：68.9±6.5岁）。根据EWGSOP-2，少肌症的患病率为21.7％，根据EWGSOP-1为55.0％。根据SARC-F，对肌肉减少症的阳性筛查率为30％，根据SARC-CalF，筛查率为36.7％。使用2010年和2019年共识的标准，SARC-F检测肌肉减少症的敏感性分别为27.2％和23.1％。对SARC-CalF的比较分析显示，通过增加小腿围长，其在诊断判别中具有更好的性能，灵敏度范围为53.8至54.5％。与使用完整问卷相比，在椅子上站立和爬楼梯的能力（69.2％）和跌倒发生（76.9％）的项目具有更高的敏感性。

结论

在分析SARC-F作为肌肉减少症的筛查工具时发现相对较低的敏感性和肌肉减少症的低估。因此，仅使用该筛查工具就无法鉴定出大量的肌肉减少症患者。SARC-CalF的性能优于SARC-F。