In recent times, there has been rapid progress and achievement in the development of nanoparticle production in a microfluidic environment. Microfluidics technology harnesses the fluid mechanics to generate nanoparticles with a unique size and finely controllable shape that can be used for various applications like drug delivery, biological sciences, healthcare, and food industries. The nanoparticles are generally distinguished from fine particles to coarse particles due to their smaller size and unique material properties like chemical, physical, biological, and optical. However, the conventional methods require bulky instruments, expensive autoclaves, consume more power, high thermal loss, and require more time for the synthesis. Further, it is very challenging to automate, integrate, and miniaturize the conventional device on a single platform for synthesizing micro-and nanoscale particles. There has been considerable advancement in the development of microfluidic devices in the last few years for nanoparticle synthesis. The microfluidic device unveils several features such as portability, transparency in operation, controllability, and stability with a marginal reaction volume. The microfluidic-based nanoparticle synthesis also allows rapid processing and increased efficiency of the technique by using minimum peripherals for its operation. In this review article, we have discussed the microfluidic devices that are used for synthesizing various nanoparticles for different applications. This review summarizes the value-chain to develop microfluidic devices, including designs, fabrication techniques, and other related methodologies, to create nanoparticles in a controlled and selective manner.

近年来，在微流体环境中开发纳米颗粒的生产已经取得了快速的进展和成就。微流体技术利用流体力学来生成具有独特尺寸和精细可控形状的纳米颗粒，可用于药物输送，生物科学，医疗保健和食品工业等各种应用。纳米粒子由于其较小的尺寸和独特的材料特性（例如化学，物理，生物学和光学特性），通常从细颗粒到粗颗粒有所区别。然而，常规方法需要笨重的仪器，昂贵的高压釜，消耗更多的功率，高的热损失并且需要更多的合成时间。此外，自动化，集成，并在单一平台上将常规设备小型化，以合成微米级和纳米级颗粒。在过去的几年中，用于纳米颗粒合成的微流体装置的开发取得了相当大的进步。该微流体装置具有一些功能，例如便携性，操作的透明性，可控制性和具有少量反应体积的稳定性。通过使用最少的外围设备进行操作，基于微流体的纳米颗粒合成还可以实现快速处理并提高技术效率。在这篇综述文章中，我们讨论了用于合成用于不同应用的各种纳米粒子的微流体装置。这篇评论总结了开发微流体装置的价值链，包括设计，制造技术，