Phytochemicals as potential Curative Agents against Viral Infection: A Review,Current Organic Chemistry

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Phytochemicals as potential Curative Agents against Viral Infection: A Review
Current Organic Chemistry ( IF 1.7 ) Pub Date : 2020-12-02 , DOI: 10.2174/1385272824999200910093524
Abhijeet Kumar ₁ , Anil Kumar Singh ₁ , Garima Tripathi ₂

Affiliation

The present pandemic erupted due to highly contagious coronavirus SARS-CoV-2, and lack of any efficient therapy to restrain its infection and treatment, led the scientific community to re-evaluate the efficacy of commonly available phytochemicals as potential therapeutic agents The vast pharmacological activities and medicinal significance of the plant-derived natural products against a diverse range of physiological disorders and diseases are well documented Under the current health emergency across the world, there is an urgent requirement of repurposing of the available FDA approved drugs and natural products which could help in controlling the infections and alleviating the severity of the diseases as discovering entirely new chemical entity as a novel drug would be a protracted and costly journey Some of the phytochemicals have already displayed potential anti-viral activity against different targets of SARS-CoV-2 virus The present review would provide an account of the prevalent phytochemicals with antiviral activities, which would help in the development of promising drug therapy for the treatment of COVID-19 and similar such highly infectious viruses © 2020 Bentham Science Publishers

中文翻译：

植物化学物质作为抗病毒感染的潜在治疗剂：综述

目前的大流行是由于高度传染性的冠状病毒 SARS-CoV-2 而爆发的，并且缺乏任何有效的疗法来抑制其感染和治疗，导致科学界重新评估常用植物化学物质作为潜在治疗剂的功效巨大的药理活性植物来源的天然产物对多种生理紊乱和疾病的药用意义和药用意义在世界各地当前的卫生紧急情况下得到充分证明，迫切需要重新利用现有的 FDA 批准的药物和天然产品，这些药物和天然产品可以帮助控制感染和减轻疾病的严重程度，因为发现全新的化学实体作为一种新药将是一个漫长而昂贵的旅程。植物化学物质已经对 SARS-CoV-2 病毒的不同靶点显示出潜在的抗病毒活性本综述将提供具有抗病毒活性的普遍植物化学物质的说明，这将有助于开发有前景的治疗 COVID- 19 和类似的此类高传染性病毒 © 2020 Bentham Science Publishers这将有助于开发有前景的药物疗法来治疗 COVID-19 和类似的此类高传染性病毒 © 2020 Bentham Science Publishers这将有助于开发有前景的药物疗法来治疗 COVID-19 和类似的此类高传染性病毒 © 2020 Bentham Science Publishers

更新日期：2020-12-02

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