Abstract

A convenient approach for the synthesis of diversely functionalized [1,2,4]triazolo[5,1-f]purine heterocyclic framework have been accomplished. The products were obtained through the combination of 5-amino-3-(methylthio)-1H-1,2,4-triazole with 5-bromo-2,4-dichloro-6-methylpyrimidine followed by a S_NAr alkoxylation of the novel tricyclic heterocyclic core with various aliphatic alcohols. All newly synthesized heterocycles were fully elucidated by both computational and spectral evaluations.

中文翻译：

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新型三环 2-烷氧基-8-甲基-6-(吡咯烷-1-基)-4H-[1,2,4]三唑并[5,1-f]嘌呤衍生物：合成与表征

一种合成不同功能化的 [1,2,4] 三唑并 [5,1-f] 嘌呤杂环骨架的简便方法已经完成。该产品是通过组合...