Autoimmune and inflammatory disorder (AIID) prevalence appears to be increasing in all but the world’s poorest regions and countries. Autoimmune diseases occur when there is a breakdown in processes that regulate inflammation and self‐recognition by immune cells. Very few field‐based studies have been conducted among Indigenous populations and underserved communities with limited access to medical care. This is due, in part, to the fact that autoimmune diseases are difficult to diagnose, even in clinical settings. In remote field settings these difficulties are compounded by the absence of infrastructure necessary for sample storage and analysis, and the lack of hospital/clinic access for more invasive diagnostic procedures. Because of these limitations, little is known about the prevalence of autoimmunity outside wealthy regions and clinical settings.

中文翻译：

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测量对自我的攻击：人类生物学中自身免疫领域现场友好方法开发和研究的需要


除世界上最贫困的地区和国家外，自身免疫性和炎症性疾病 (AIID) 的患病率似乎都在增加。当免疫细胞调节炎症和自我识别的过程发生故障时，就会发生自身免疫性疾病。在土著居民和医疗服务水平有限的服务欠缺社区中进行的实地研究非常少。部分原因是自身免疫性疾病即使在临床环境中也难以诊断。在偏远地区，由于缺乏样本存储和分析所需的基础设施，以及缺乏医院/诊所进行更具侵入性的诊断程序，这些困难变得更加复杂。由于这些限制，人们对富裕地区和临床环境之外的自身免疫性疾病的流行情况知之甚少。