D‐limonene: A multifunctional compound with potent therapeutic effects,Journal of Food Biochemistry

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D‐limonene: A multifunctional compound with potent therapeutic effects
Journal of Food Biochemistry ( IF 3.5 ) Pub Date : 2020-12-01 , DOI: 10.1111/jfbc.13566
Pandi Anandakumar ₁ , Sattu Kamaraj ₂ , Manickam Kalappan Vanitha ₃

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D‐limonene or 4‐isopropenyl‐1‐methylcyclohexene (C₁₀H₁₆) is a monocyclic monoterpene abundant in citrus plants like lemon, orange, and grape. The application of D‐limonene in the form of flavor and fragrance additive in perfumes, soaps, foods, and beverages is consistently increased due to its high‐quality fragrance property. This review is intended to analyze and delineate every possible available evidence and details about D‐limonene with the special focus on its therapeutic efficacy. Many studies have reported that D‐limonene effectively plays a valuable role in the prevention of several chronic and degenerative diseases. This review provides worthy information about the beneficial effects of D‐limonene such as antioxidant, antidiabetic, anticancer, anti‐inflammatory, cardioprotective, gastroprotective, hepatoprotective, immune modulatory, anti‐fibrotic, anti‐genotoxic etc. This could in turn help in the application of D‐limonene for clinical studies.

中文翻译：

D-柠檬烯：具有有效治疗作用的多功能化合物

D-柠檬烯或4-异丙烯基-1-甲基环己烯（C ₁₀ H ₁₆）是一种单环单萜，在柑橘类植物（如柠檬，橙和葡萄）中富集。由于其高质量的香气特性，以香料和香精添加剂形式存在的D-柠檬烯在香水，肥皂，食品和饮料中的应用一直在增加。这篇综述旨在分析和描述关于D-柠檬烯的所有可能的证据和细节，并特别关注其治疗功效。许多研究报告说，D-柠檬烯在预防几种慢性和退行性疾病中起着重要作用。这篇综述提供了有关D-柠檬烯有益作用的有价值信息，例如抗氧化剂，抗糖尿病药，抗癌药，抗炎药，心脏保护药，胃保护药，肝保护药，免疫调节剂，抗纤维化药，抗基因毒性药等。

更新日期：2021-01-19

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