Nematode Chemosensory G-Protein Coupled Receptors have expanded within nematodes, where they play important roles in foraging and host-seeking behaviour. Nematode Chemosensory G-Protein Coupled Receptors are most highly expressed during free-living stages when chemosensory signalling is required for host detection and nematode activation in various parasitic nematodes, and therefore position Nematode Chemosensory G-Protein Coupled Receptors at the transition from infective to parasitic stages, making them important regulators to study in terms of host-seeking and host specificity. To facilitate the analysis of Nematode Chemosensory G-Protein Coupled Receptors, here we describe an integrative database of nematode chemoreceptors called NemChR-DB. This database enables users to study diverse parasitic nematode chemoreceptors, functionally explore sequence entries through structural and literature-based annotations, and perform cross-species comparisons.

线虫化学感觉 G 蛋白偶联受体已在线虫中扩展，它们在觅食和寻找宿主行为中发挥重要作用。线虫化学感应 G 蛋白偶联受体在自由生活阶段表达最高，此时在各种寄生线虫中宿主检测和线虫激活需要化学感应信号传导，因此将线虫化学感应 G 蛋白偶联受体定位在从感染阶段到寄生阶段的过渡阶段，使它们成为研究宿主寻找和宿主特异性方面的重要监管者。为了便于分析线虫化学感觉 G 蛋白偶联受体，我们在这里描述了一个名为 NemChR-DB 的线虫化学受体综合数据库。该数据库使用户能够研究各种寄生线虫化学感受器，