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Improved Breast Cancer Classification Through Combining Graph Convolutional Network and Convolutional Neural Network
Information Processing & Management ( IF 7.4 ) Pub Date : 2020-12-02 , DOI: 10.1016/j.ipm.2020.102439
Yu-Dong Zhang , Suresh Chandra Satapathy , David S. Guttery , Juan Manuel Górriz , Shui-Hua Wang

Aim

In a pilot study to improve detection of malignant lesions in breast mammograms, we aimed to develop a new method called BDR-CNN-GCN, combining two advanced neural networks: (i) graph convolutional network (GCN); and (ii) convolutional neural network (CNN).

Method

We utilised a standard 8-layer CNN, then integrated two improvement techniques: (i) batch normalization (BN) and (ii) dropout (DO). Finally, we utilized rank-based stochastic pooling (RSP) to substitute the traditional max pooling. This resulted in BDR-CNN, which is a combination of CNN, BN, DO, and RSP. This BDR-CNN was hybridized with a two-layer GCN, and yielded our BDR-CNN-GCN model which was then utilized for analysis of breast mammograms as a 14-way data augmentation method.

Results

As proof of concept, we ran our BDR-CNN-GCN algorithm 10 times on the breast mini-MIAS dataset (containing 322 mammographic images), achieving a sensitivity of 96.20±2.90%, a specificity of 96.00±2.31% and an accuracy of 96.10±1.60%.

Conclusion

Our BDR-CNN-GCN showed improved performance compared to five proposed neural network models and 15 state-of-the-art breast cancer detection approaches, proving to be an effective method for data augmentation and improved detection of malignant breast masses.



中文翻译:

结合图卷积网络和卷积神经网络改进乳腺癌分类

目标

在一项旨在改善对乳房X线照片中的恶性病变的检测的初步研究中,我们旨在开发一种称为BDR-CNN-GCN的新方法,该方法结合了两个高级神经网络:(i)图卷积网络(GCN);(ii)卷积神经网络(CNN)。

方法

我们使用了标准的8层CNN,然后集成了两种改进技术:(i)批处理规范化(BN)和(ii)退出(DO)。最后,我们利用基于等级的随机池(RSP)代替了传统的最大池。这导致了BDR-CNN,它是CNN,BN,DO和RSP的组合。将此BDR-CNN与两层GCN杂交,得到我们的BDR-CNN-GCN模型,然后将其作为14方向数据增强方法用于乳房X线照片的分析。

结果

作为概念验证,我们在乳腺mini-MIAS数据集(包含322个乳腺X线照片)上运行了10次BDR-CNN-GCN算法,灵敏度为96.20±2.90%,特异性为96.00±2.31%,准确度为96.10±1.60%。

结论

与五种建议的神经网络模型和15种最新的乳腺癌检测方法相比,我们的BDR-CNN-GCN表现出更高的性能,被证明是一种有效的数据增强方法和改进的恶性乳腺肿块检测方法。

更新日期:2020-12-02
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