当前位置：
X-MOL 学术
›
Eye and Vis.
›
论文详情
Our official English website, www.x-mol.net, welcomes your
feedback! (Note: you will need to create a separate account there.)
The associations of lens power with age, axial length and type 2 diabetes mellitus in Chinese adults aged 50 and above
Eye and Vision ( IF 4.1 ) Pub Date : 2020-12-01 , DOI: 10.1186/s40662-020-00222-2 Luyao Ye , Jiangnan He , Xinji Zhang , Yi Xu , Qiuying Chen , Yao Yin , Ying Fan , Lina Lu , Jianfeng Zhu , Haidong Zou , Xun Xu
Eye and Vision ( IF 4.1 ) Pub Date : 2020-12-01 , DOI: 10.1186/s40662-020-00222-2 Luyao Ye , Jiangnan He , Xinji Zhang , Yi Xu , Qiuying Chen , Yao Yin , Ying Fan , Lina Lu , Jianfeng Zhu , Haidong Zou , Xun Xu
To investigate the associations of lens power with age, axial length (AL), and Type 2 diabetes mellitus (DM) in Chinese adults aged 50 and above. Random clustering sampling was used to identify adults aged 50 years and above in urban regions of Shanghai. The participants underwent a comprehensive ophthalmic examination including subjective refraction, autorefraction, and IOL-Master. The crystalline lens power was calculated using Bennett’s formula. A total of 4177 adults were included. A linear decrease in lens power was observed both with age and with AL, followed by a stop of lens power loss after the age of 70 or when AL ≥ 25 mm, respectively. Participants with Type 2 DM presented higher lens power (0.43 diopter (D), p < 0.001) and thicker lens thickness (0.06 mm, p < 0.001). In multivariate regression models, there was a positive correlation between lens power and Type 2 DM when age < 75 years (p < 0.001) or AL < 25 mm (p < 0.001) after adjusting for other factors, while no significant association was found in participants aged ≥ 75 years (p = 0.122) or with AL ≥ 25 mm (p = 0.172). The lens power in adults aged 50 and above exhibited two stages with age and with AL. Type 2 DM caused an increase in lens power, which was not seen in participants aged ≥ 75 years or with AL ≥ 25 mm.
更新日期：2020-12-01
京公网安备 11010802027423号