Single-molecule experiments reveal structure function relationships and biomolecular dynamics in physiologically relevant conditions. In this issue of Structure, Park et al. (2020) report an optimized surface passivation strategy with polyethylene glycol in a dense, contracted conformation. Assembly of a functional transcription pre-initiation complex is demonstrated.

中文翻译：

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单分子批准的表面钝化

单分子实验揭示了生理相关条件下的结构功能关系和生物分子动力学。在本期《结构》中，Park等人。（2020年）报告了一种优化的表面钝化策略，其中聚乙二醇具有致密，收缩的构象。演示了功能性转录预起始复合物的组装。