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OGDA: a comprehensive organelle genome database for algae
Database: The Journal of Biological Databases and Curation ( IF 3.4 ) Pub Date : 2020-11-28 , DOI: 10.1093/database/baaa097
Tao Liu 1, 2, 3 , Yutong Cui 1 , Xuli Jia 2 , Jing Zhang 4 , Ruoran Li 1 , Yahui Yu 2 , Shangang Jia 5 , Jiangyong Qu 1 , Xumin Wang 1
Affiliation  

Algae are the oldest taxa on Earth, with an evolutionary relationship that spans prokaryotes (Cyanobacteria) and eukaryotes. A long evolutionary history has led to high algal diversity. Their organelle DNAs are characterized by uniparental inheritance and a compact genome structure compared with nuclear genomes; thus, they are efficient molecular tools for the analysis of gene structure, genome structure, organelle function and evolution. However, an integrated organelle genome database for algae, which could enable users to both examine and use relevant data, has not previously been developed. Therefore, to provide an organelle genome platform for algae, we have developed a user-friendly database named Organelle Genome Database for Algae (OGDA, http://ogda.ytu.edu.cn/). OGDA contains organelle genome data either retrieved from several public databases or sequenced in our laboratory (Laboratory of Genetics and Breeding of Marine Organism [MOGBL]), which are continuously updated. The first release of OGDA contains 1055 plastid genomes and 755 mitochondrial genomes. Additionally, a variety of applications have been integrated into this platform to analyze the structural characteristics, collinearity and phylogeny of organellar genomes for algae. This database represents a useful tool for users, enabling the rapid retrieval and analysis of information related to organellar genomes for biological discovery.

中文翻译:

OGDA:藻类综合细胞器基因组数据库

藻类是地球上最古老的分类群,其进化关系跨越原核生物(蓝藻)和真核生物。漫长的进化历史导致了高度的藻类多样性。与核基因组相比,它们的细胞器DNA具有单亲遗传和紧凑的基因组结构;因此,它们是分析基因结构、基因组结构、细胞器功能和进化的有效分子工具。然而,之前还没有开发出一个集成的藻类细胞器基因组数据库,它可以让用户检查和使用相关数据。因此,为了提供藻类细胞器基因组平台,我们开发了一个名为“藻类细胞器基因组数据库”(OGDA,http://ogda.ytu.edu.cn/)的用户友好型数据库。OGDA 包含从多个公共数据库检索或在我们的实验室(海洋生物遗传学和育种实验室 [MOGBL])中测序的细胞器基因组数据,这些数据不断更新。OGDA 的第一个版本包含 1055 个质体基因组和 755 个线粒体基因组。此外,该平台还集成了多种应用程序,以分析藻类细胞器基因组的结构特征、共线性和系统发育。该数据库为用户提供了一个有用的工具,能够快速检索和分析与生物发现的细胞器基因组相关的信息。OGDA 的第一个版本包含 1055 个质体基因组和 755 个线粒体基因组。此外,该平台还集成了多种应用程序,以分析藻类细胞器基因组的结构特征、共线性和系统发育。该数据库为用户提供了一个有用的工具,能够快速检索和分析与生物发现的细胞器基因组相关的信息。OGDA 的第一个版本包含 1055 个质体基因组和 755 个线粒体基因组。此外,该平台还集成了多种应用程序,以分析藻类细胞器基因组的结构特征、共线性和系统发育。该数据库为用户提供了一个有用的工具,能够快速检索和分析与生物发现的细胞器基因组相关的信息。
更新日期:2020-12-01
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