N-(2-hydroxyl) propyl-3-trimethyl ammonium chitosan chloride (HTCC) was synthesized with chitosan and 2,3-epoxypropyl trimethyl ammonium chloride. Moreover, the grafted acrylamide copolymer (HTCC-VMT-PAM) was synthesized with HTCC, vermiculite (VMT) and acrylamide (AM). The antibacterial test results demonstrated that HTCC-VMT-PAM had significant biological antibacterial activity, and the inhibition area against Aspergillus, Penicillium, Alternaria alternate, Staphylococcus aureus and Escherichia coli were 1.90 ± 0.14, 2.20 ± 0.15, 5.20 ± 1.07, 27.97 ± 1.42 and 37.69 ± 1.09 cm², respectively. Moreover, poly(lactic acid) (PLA)/HTCC-VMT-PAM nanocomposites were prepared using PLA and various contents of HTCC-VMT-PAM as fillers. The mechanical testing results showed that the tensile strength, elongation at break and impact strength of PLA/HTCC-VMT-PAM nanocomposites were increased by 11.48%, 10.48% and 33.98%, respectively, higher than that of pure PLA when the addition amount of HTCC-VMT-PAM was 0.7 wt%. Owing to the strong heterogeneous nucleation of HTCC-VMT-PAM, it induced rapid crystallization of PLA and improved the crystallinity of PLA to 41.97%. Rheological behavior showed that HTCC-VMT-PAM and PLA matrix had strong compatibility. Enzymatic degradation behavior showed that the addition of HTCC-VMT-PAM had some inhibition effect on the biodegradability of PLA.

用壳聚糖和2,3-环氧丙基三甲基氯化铵合成了N-（2-羟基）丙基-3-三甲基氯化铵壳聚糖（HTCC）。此外，用HTCC，ver石（VMT）和丙烯酰胺（AM）合成了接枝丙烯酰胺共聚物（HTCC-VMT-PAM）。抗菌测试结果表明，HTCC-VMT-PAM具有明显的生物抗菌活性，对曲霉菌，青霉菌，交替链霉菌，金黄色葡萄球菌和大肠杆菌的抑制面积分别为1.90±0.14、2.20±0.15、5.20±1.07、27.97±1.42。和37.69±1.09 cm ²， 分别。此外，使用PLA和各种含量的HTCC-VMT-PAM作为填料，制备了聚乳酸（PLA）/ HTCC-VMT-PAM纳米复合材料。力学测试结果表明，PLA / HTCC-VMT-PAM纳米复合材料的拉伸强度，断裂伸长率和冲击强度分别比纯PLA提高了11.48％，10.48％和33.98％。 HTCC-VMT-PAM为0.7重量％。由于HTCC-VMT-PAM的强烈异质成核作用，它诱导了PLA的快速结晶，并使PLA的结晶度提高到41.97％。流变行为表明HTCC-VMT-PAM与PLA基质具有很强的相容性。酶促降解行为表明，加入HTCC-VMT-PAM对PLA的生物降解性有一定的抑制作用。