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Successful hematopoietic stem cell transplantation in a 4-1BB deficient patient with EBV-induced lymphoproliferation
Clinical Immunology ( IF 4.5 ) Pub Date : 2020-11-28 , DOI: 10.1016/j.clim.2020.108639
Christine Wildermann 1 , Mohammed Alosaimi 2 , Sophie Liebenehm 1 , Eva-Maria Jacobsen 1 , Thomas F E Barth 3 , Peter Möller 3 , Klaus-Michael Debatin 1 , Ansgar Schulz 1 , Mehtap Sirin 1 , Ibraheem F Abosoudah 4 , Fowzan S Alkuraya 5 , Raif S Geha 6 , Manfred Hönig 1
Affiliation  

Complete remission from recurrent EBV-positive lymphoma is not mandatory before HSCT to achieve long-term cure in a patient suffering from a recently described immunodeficiency affecting the T-cell coactivation molecule 4-1BB.



中文翻译:

4-1BB缺陷型EBV诱导的淋巴组织增生患者成功进行造血干细胞移植

在患有最近描述的影响 T 细胞共激活分子 4-1BB 的免疫缺陷的患者中,在 HSCT 之前不需要完全缓解复发性EBV阳性淋巴瘤以获得长期治愈。

更新日期:2020-12-04
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