当前位置: X-MOL 学术Nanotechnol. Rev. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Braided composite stent for peripheral vascular applications
Nanotechnology Reviews ( IF 6.1 ) Pub Date : 2020-11-27 , DOI: 10.1515/ntrev-2020-0056
Qingli Zheng 1 , Pengfei Dong 2 , Zhiqiang Li 3 , Ying Lv 1 , Meiwen An 1 , Linxia Gu 2
Affiliation  

Abstract Braided composite stent (BCS), woven with nitinol wires and polyethylene terephthalate (PET) strips, provides a hybrid design of stent. The mechanical performance of this novel stent has not been fully investigated yet. In this work, the influence of five main design factors (number of nitinol wires, braiding angle, diameter of nitinol wire, thickness and stiffness of the PET strip) on the surface coverage, radial strength, and flexibility of the BCS were systematically studied using computational models. The orthogonal experimental design was adopted to quantitatively analyze the sensitivity of multiple factors using the minimal number of study cases. Results have shown that the nitinol wire diameter and the braiding angle are two most important factors determining the mechanical performance of the BCS. A larger nitinol wire diameter led to a larger radial strength and less flexibility of the BCS. A larger braiding angle could provide a larger radial strength and better flexibility. In addition, the impact of the braiding angle decreased when the stent underwent a large deformation. At the same time, the impact of the PET strips increased due to the interaction with nitinol wires. Moreover, the number of PET strips played an important role in the surface coverage. This study could help understand the mechanical performance of BCS stent and provides guidance on the optimal design of the stent targeting less complications.

中文翻译:


用于外周血管应用的编织复合支架



摘要 编织复合支架(BCS)由镍钛诺丝和聚对苯二甲酸乙二醇酯(PET)带编织而成,提供了一种混合设计的支架。这种新型支架的机械性能尚未得到充分研究。在这项工作中,系统地研究了五个主要设计因素(镍钛诺丝的数量、编织角度、镍钛诺丝的直径、PET带材的厚度和刚度)对BCS的表面覆盖率、径向强度和柔性的影响,计算模型。采用正交实验设计,以最少的研究例数定量分析多因素的敏感性。结果表明,镍钛诺丝直径和编织角度是决定BCS机械性能的两个最重要因素。镍钛诺丝直径越大,BCS 的径向强度越大,灵活性越差。较大的编织角度可以提供较大的径向强度和更好的柔韧性。此外,当支架发生较大变形时,编织角的影响减小。同时,由于与镍钛诺丝的相互作用,PET 条的影响增加。此外,PET条的数量对表面覆盖率起着重要作用。这项研究有助于了解BCS支架的机械性能,并为减少并发症的支架优化设计提供指导。
更新日期:2020-11-27
down
wechat
bug