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Multiday cycles of heart rate are associated with seizure likelihood
medRxiv - Neurology Pub Date : 2021-08-15 , DOI: 10.1101/2020.11.24.20237990
Philippa J. Karoly , Rachel E. Stirling , Dean R. Freestone , Ewan S. Nurse , Matias Maturana , Amy Halliday , Andrew Neal , Nicholas M. Gregg , Benjamin Brinkmann , Mark P. Richardson , Sonya B. Dumanis , Andre La Gerche , David B. Grayden , Wendyl D’Souza , Mark J. Cook

Circadian and multiday rhythms are found across many biological systems, including cardiology, endocrinology, neurology, and immunology. In people with epilepsy, epileptic brain activity and seizure occurrence have been found to follow circadian, weekly, and monthly rhythms. Understanding the relationship between these cycles of brain excitability and other physiological systems can provide new insight into the causes of multiday cycles. The brain-heart link is relevant for epilepsy, with implications for seizure forecasting, therapy, and mortality (i.e., sudden unexpected death in epilepsy).

中文翻译:

心率的多天周期与癫痫发作的可能性有关

昼夜节律和多日节律存在于许多生物系统中,包括心脏病学、内分泌学、神经学和免疫学。在癫痫患者中,已发现癫痫大脑活动和癫痫发作遵循昼夜节律、每周节律和每月节律。了解这些大脑兴奋性周期与其他生理系统之间的关系可以提供对多日周期原因的新见解。脑心联系与癫痫相关,对癫痫发作预测、治疗和死亡率(即癫痫中的突然意外死亡)有影响。
更新日期:2021-08-17
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