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Many XCI-ting routes to reach the eXACT dose
Nature Cell Biology ( IF 17.3 ) Pub Date : 2020-11-30 , DOI: 10.1038/s41556-020-00608-3
Jean-François Ouimette , Claire Rougeulle

X-chromosome inactivation studies have revealed striking species specificities in terms of the players, kinetics and mechanisms. Transcriptomic profiling of human pre‐implantation development and germ cell differentiation suggests a peculiar dosage compensation mechanism with yet undefined contributions from XIST and XACT lncRNAs.

中文翻译:

许多XCI-ting途径可达到eXACT剂量

X染色体灭活研究已经揭示了在球员,动力学和机制方面惊人的物种特异性。人体植入前发育和生殖细胞分化的转录组分析表明,一种特殊的剂量补偿机制,而XIST和XACT lncRNA的贡献尚未明确。
更新日期:2020-12-01
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