ABSTRACT

Objectives: This study was conducted to assess the reporting quality of health economic evaluation studies using Consolidated Health Economic Evaluation Reporting Standards (CHEERS) statement along with an analysis of their trend in India.

Methods: Following ethical review exemption, PubMed and Google scholar were searched for Indian studies published in 5 years (2014–2019). Keywords used were cost-effectiveness, cost-benefit, cost-utility, and cost-minimization analysis, economic evaluation, and India. CHEERS statement was used to assess the reporting quality and trend was studied using variables like a published year, type of analysis, therapy area, intervention. Data were analyzed using descriptive statistics.

Results: Of the 39 studies analyzed, 17 scored less than 18 (represents 75% compliance) with a minimum score of 9 and a maximum of 23. The reporting quality was deficient with respect to heterogeneity characterization (25 studies), discount rate (18 studies), model choice, and assumptions (18 studies). Cost – effectiveness was the most common PE analysis (27 studies). The most commonly studied therapy area was infectious disorders (10) followed by oncology (5), and the commonest intervention was drugs (22).

Conclusion: Inadequacy in reporting quality of health economic evaluation studies is evident. The trend revealed cost-effectiveness to be the most commonly performed type of analysis.

Expert Opinion: Health economic evaluation research has gained considerable importance in healthcare decision making. Reporting quality is critical to enable efficient interpretation of health economic evaluation research. These studies have many elements, each of which have a significant impact on the conduct and outcome of the study. Hence, it is advisable to refer to any of the available guidelines [eg. CHEERS checklist] while preparing the manuscript so as to ensure all crucial elements of the study have been reported.

摘要

目标：本研究旨在使用综合卫生经济评估报告标准 (CHEERS) 声明评估卫生经济评估研究的报告质量，并分析其在印度的趋势。

方法：遵循伦理审查豁免，在 PubMed 和 Google 学者中搜索 5 年（2014-2019 年）发表的印度研究。使用的关键词是成本效益、成本效益、成本效用和成本最小化分析、经济评估和印度。CHEERS 声明用于评估报告质量，并使用诸如出版年份、分析类型、治疗领域、干预等变量来研究趋势。使用描述性统计分析数据。

结果：在分析的 39 项研究中，17 项得分低于 18（代表 75% 的依从性），最低得分为 9，最高得分为 23。报告质量在异质性表征（25 项研究）、贴现率（18研究）、模型选择和假设（18 项研究）。成本 - 效果是最常见的 PE 分析（27 项研究）。最常研究的治疗领域是感染性疾病（10），其次是肿瘤学（5），最常见的干预是药物（22）。

结论：卫生经济评价研究报告质量的不足是显而易见的。趋势表明，成本效益是最常用的分析类型。

专家意见：卫生经济评价研究在医疗决策中具有相当重要的意义。报告质量对于有效解释卫生经济评估研究至关重要。这些研究有许多要素，每一个要素都对研究的实施和结果产生重大影响。因此，建议参考任何可用的指南 [例如。CHEERS 清单] 在准备手稿时，以确保研究的所有关键要素都已报告。