Abstract

Objectives To adapt and test the feasibility, acceptability, and preliminary efficacy of an 8-week resiliency group program for posttreatment lymphoma survivors.

Design and outcomes. This is an exploratory mixed methods study. Phase 1: We conducted qualitative interviews to inform program adaptation. Phase 2: Using a single-arm pilot design, we assessed program feasibility, acceptability, and preliminary efficacy (exploratory outcomes: stress coping, uncertainty intolerance, distress). We also examined the feasibility of collecting hair cortisol samples.

Results. Phase 1: Survivors reported feeling socially isolated as they grappled with lingering symptoms that interfered with their return to normalcy. Fears about recurrence triggered bodily hypervigilance. Survivors desired wellness programs that 1) target their whole-body experience, 2) promote social connectedness, and 3) manage fear of recurrence. Phase 2: Thirty-seven survivors enrolled. Participants completed a median of 7/8 sessions, and 76.9% completed ≥6/8 sessions; 65% provided a hair sample. Survivors demonstrated improvements in stress coping (d = .67), uncertainty tolerance (d = .71), and anxiety (d = .41) at program completion.

Conclusions. Findings suggest promising feasibility and efficacy of this program in addressing posttreatment survivorship challenges, particularly fears of uncertainty. A cancer care model that adopts early integration of this program posttreatment has the potential to improve survivors’ emotional, social and physical well-being.

摘要

目的调整和测试针对治疗后淋巴瘤幸存者的 8 周弹性小组计划的可行性、可接受性和初步疗效。

设计和成果。这是一项探索性的混合方法研究。第 1 阶段：我们进行了定性访谈以告知项目适应情况。第 2 阶段：使用单臂试验设计，我们评估了项目的可行性、可接受性和初步效果（探索性结果：压力应对、不确定性不耐受、痛苦）。我们还研究了收集头发皮质醇样本的可行性。

结果。第 1 阶段：幸存者报告说，当他们努力应对影响他们恢复正常的挥之不去的症状时，他们感到被社会孤立。对复发的恐惧引发了身体的过度警觉。幸存者希望健康计划 1）针对他们的全身体验，2）促进社会联系，以及 3）管理对复发的恐惧。第 2 阶段：37 名幸存者入组。参与者完成中位数为 7/8 次，76.9% 完成≥6/8 次；65% 提供了头​​发样本。幸存者在项目完成时表现出在压力应对 (d = .67)、不确定性耐受性 (d = .71) 和焦虑 (d = .41) 方面的改善。

结论。研究结果表明，该计划在解决治疗后生存挑战方面具有前景的可行性和有效性，尤其是对不确定性的恐惧。采用该计划后治疗的早期整合的癌症护理模式有可能改善幸存者的情绪、社会和身体健康。