Adaptivity and dynamics in type III secretion systems,Molecular Microbiology

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Adaptivity and dynamics in type III secretion systems
Molecular Microbiology ( IF 2.6 ) Pub Date : 2020-11-29 , DOI: 10.1111/mmi.14658
Bailey Milne-Davies ₁ , Stephan Wimmi ₁ , Andreas Diepold ₁

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The type III secretion system is the common core of two bacterial molecular machines: the flagellum and the injectisome. The flagellum is the most widely distributed prokaryotic locomotion device, whereas the injectisome is a syringe‐like apparatus for inter‐kingdom protein translocation, which is essential for virulence in important human pathogens. The successful concept of the type III secretion system has been modified for different bacterial needs. It can be adapted to changing conditions, and was found to be a dynamic complex constantly exchanging components. In this review, we highlight the flexibility, adaptivity, and dynamic nature of the type III secretion system.

中文翻译：

III 型分泌系统的适应性和动力学

III型分泌系统是两种细菌分子机器的共同核心：鞭毛和注射体。鞭毛是分布最广泛的原核运动装置，而注射体是用于跨界蛋白质易位的注射器样装置，这对于重要的人类病原体的毒力至关重要。III 型分泌系统的成功概念已针对不同的细菌需求进行了修改。它可以适应不断变化的条件，并被发现是一个不断交换组件的动态复合体。在这篇综述中，我们强调了 III 型分泌系统的灵活性、适应性和动态特性。

更新日期：2020-11-29

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