Hypertension is a rare complication of Leigh Syndrome (LS), but prognosis of patients with hypertension is poor and its presence is indicative of the terminal stage of the disease. Herein, we report a four-year-old girl case diagnosed with LS at 15 months of age who subsequently developed severe hypertension and respiratory failure. Physical examination and laboratory findings did not indicate a secondary cause of hypertension. Her respiratory failure was treated with non-invasive ventilation and hypertension controlled with enalapril, furosemide and spironolactone. To our knowledge, this is the first case of a patient with LS recovering from severe hypertension.

高血压是 Leigh 综合征 (LS) 的一种罕见并发症，但高血压患者的预后很差，它的存在表明该病已进入末期。在此，我们报告了一个在 15 个月大时被诊断为 LS 的 4 岁女孩病例，她随后发展为严重的高血压和呼吸衰竭。体格检查和实验室检查结果并未提示高血压的次要原因。她的呼吸衰竭接受了无创通气治疗，并用依那普利、呋塞米和螺内酯控制了高血压。据我们所知，这是首例从严重高血压中恢复的 LS 患者。