Adult neurogenesis has been reported in all major vertebrate taxa. However, neurogenic rates and the number of neurogenic foci vary greatly, and are higher in ancestral taxa. Our study aimed to evaluate the distribution of doublecortin (DCX) and glial fibrillary acidic protein (GFAP) in telencephalic areas of the adult tropical lizard Tropidurus hispidus. We describe evidence for four main neurogenic foci, which coincide anatomically with the ventricular sulci described by the literature. Based on neuronal morphology, we infer four migratory patterns/pathways. In the cortex, patterns of GFAP and DCX staining support radial migrations from ventricular zones into cortical areas and dorsoventricular ridge. Cells radiating from the sulcus septomedialis (SM) seemed to migrate to the medial cortex and dorsal cortex. From the sulcus lateralis (SL), they seemed to be bound for the lateral cortex, central amygdala and nucleus sphericus. We describe a DCX-positive stream originating in the caudal sulcus ventralis and seemingly bound for the olfactory bulb, resembling a rostral migratory stream. We provide evidence for a previously undescribed tangential dorso-septo-caudal migratory stream, with neuroblasts supported by DCX-positive fibers. Finally, we provide evidence for a commissural migration stream seemingly bound for the contralateral nucleus sphericus. Therefore, in addition to two previously known migratory streams, this study provides anatomical evidence in support for two novel migratory routes in amniotes.

中文翻译：

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双皮质素和胶质纤维酸性蛋白的端脑分布表明成年蜥蜴的新迁移途径

在所有主要脊椎动物分类群中都报告了成体神经发生。然而，神经源性率和神经源性病灶的数量差异很大，并且在祖先分类群中更高。我们的研究旨在评估双皮质素 (DCX) 和胶质纤维酸性蛋白 (GFAP) 在成年热带蜥蜴 Tropidurus hispidus 端脑区的分布。我们描述了四个主要神经源性病灶的证据，它们在解剖学上与文献中描述的心室沟吻合。基于神经元形态，我们推断出四种迁移模式/途径。在皮质中，GFAP 和 DCX 染色的模式支持从心室区径向迁移到皮质区和背侧脊。从 septomedialis (SM) 放射的细胞似乎迁移到内侧皮质和背侧皮质。从外侧沟（SL），它们似乎与外侧皮层、中央杏仁核和球核结合。我们描述了 DCX 阳性流，起源于尾侧沟腹侧，似乎绑定到嗅球，类似于喙迁移流。我们为以前未描述的切向背-中-尾迁移流提供证据，神经母细胞由 DCX 阳性纤维支持。最后，我们为似乎绑定到对侧球核的连合迁移流提供了证据。因此，除了之前已知的两条迁徙流外，本研究还提供了解剖学证据，支持羊膜动物的两条新迁徙路线。我们描述了 DCX 阳性流，起源于尾侧沟腹侧，似乎绑定到嗅球，类似于喙迁移流。我们为以前未描述的切向背-中-尾迁移流提供证据，神经母细胞由 DCX 阳性纤维支持。最后，我们为似乎绑定到对侧球核的连合迁移流提供了证据。因此，除了之前已知的两条迁徙流外，本研究还提供了解剖学证据，支持羊膜动物的两条新迁徙路线。我们描述了 DCX 阳性流，起源于尾侧沟腹侧，似乎绑定到嗅球，类似于喙迁移流。我们为以前未描述的切向背-中-尾迁移流提供证据，神经母细胞由 DCX 阳性纤维支持。最后，我们为似乎绑定到对侧球核的连合迁移流提供了证据。因此，除了之前已知的两条迁徙流外，本研究还提供了解剖学证据，支持羊膜动物的两条新迁徙路线。我们提供了一个看似绑定到对侧球核的连合迁移流的证据。因此，除了之前已知的两条迁徙流外，本研究还提供了解剖学证据，支持羊膜动物的两条新迁徙路线。我们提供了一个看似绑定到对侧球核的连合迁移流的证据。因此，除了之前已知的两条迁徙流外，本研究还提供了解剖学证据，支持羊膜动物的两条新迁徙路线。