Silk fibroin is a unique protein polymer with broad potential for medical applications. Fibroin is significantly degraded and the materials obtained from it have poor mechanical characteristics if silk fiber is dissolved in traditional solvents. The present work used gel electrophoresis to study the dissolution of fibroin in ionic liquids. Fibroin degradation was shown to increase with increasing temperature and dissolution time. The optimal conditions for dissolution that allowed the heavy and light chains of fibroin to be preserved intact were proposed.

中文翻译：

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离子液体溶解过程中丝素蛋白分子量的变化

丝素蛋白是一种独特的蛋白质聚合物，具有广阔的医疗应用潜力。如果丝纤维溶解在传统溶剂中，纤维蛋白会被严重降解，并且从纤维蛋白中获得的材料的机械性能会很差。本工作使用凝胶电泳来研究纤维蛋白在离子液体中的溶解。丝蛋白降解显示出随着温度和溶解时间的增加而增加。提出了使丝蛋白的重链和轻链完整保留的最佳溶解条件。