BACKGROUND:The left coronary artery commonly known as LCA gets divided into two branches, such as the left circumflex (LCX) and left anterior descending (LAD) at a particular angle. This angle is varies from person to person. The present computational study contributes remarkable expertise about the influence of this angle variation on the hemodynamic parameters in the presence of 80% area stenosis at the LAD branch. OBJECTIVE:This study aimed to compare the effect of the bifurcation angle on hemodynamic parameters in the left coronary artery with 80% stenosis. METHOD:Computational models of left coronary bifurcation angles of 30°, 60°, 90°, 120° were developed to understand the flow behavior of left coronary artery branches. The 80% area stenosis (AS) is considered at the LAD branch immediate to bifurcation. RESULTS:Measurements of pressure, velocity and wall shear stress were carried out corresponding to various bifurcation angles. It was found that the drop-in pressure increases as the angle increases from narrow to wider. A slight elevation in the velocity at the stenosis was observed. In addition, the obtained results further reveal a recirculation region immediately after the plaque, which leads to more deposition of plaque in the flow obstructed area. It is known that the shear stress at the arterial wall across the stenosis increases as the angle of bifurcation increases from narrow to wider. CONCLUSIONS:The bifurcation of the left coronary artery and size of the stenosis have a notable impact on the pressure and wall shear stress. These two factors should be given due consideration by cardiologists to assess the complexity of stenosis in the LCA branches.

中文翻译：

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左冠状动脉狭窄分叉角的影响：CFD分析

背景：俗称LCA的左冠状动脉在特定角度分为左回旋支（LCX）和左前降支（LAD）两个分支。这个角度因人而异。目前的计算研究提供了关于在 LAD 分支存在 80% 区域狭窄的情况下这种角度变化对血流动力学参数的影响的非凡专业知识。目的：本研究旨在比较分叉角度对80%狭窄左冠状动脉血流动力学参数的影响。方法：建立左冠状动脉分叉角30°、60°、90°、120°的计算模型，以了解左冠状动脉分支的血流行为。80% 面积狭窄 (AS) 被认为是在 LAD 分支直接分叉处。结果：压力测量，对应于不同的分叉角进行速度和壁面剪切应力。发现压降随着角度从窄到宽的增加而增加。观察到狭窄处的速度略有升高。此外，所获得的结果进一步揭示了紧接在斑块之后的再循环区域，这导致更多的斑块沉积在流动受阻区域。众所周知，随着分叉角从窄到宽的增加，穿过狭窄的动脉壁处的剪切应力增加。结论：左冠状动脉分叉和狭窄的大小对压力和壁剪切应力有显着影响。心脏病专家应适当考虑这两个因素，以评估 LCA 分支狭窄的复杂性。