Ginseng is one of the most widely consumed herbs in the world and plays an important role in counteracting fatigue and alleviating stress. The main active substances of ginseng are its ginsenosides. Ocotillol-type triterpenoid is a remarkably effective ginsenoside from Vietnamese ginseng that has received attention because of its potential antibacterial, anticancer and anti-inflammatory properties, among others. The semisynthesis, modification and biological activities of ocotillol-type compounds have been extensively studied in recent years. The aim of this review is to summarize semisynthesis, modification and pharmacological activities of ocotillol-type compounds. The structure–activity relationship studies of these compounds were reported. This summary should prove useful information for drug exploration of ocotillol-type derivatives.

中文翻译：

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奥克替醇型三萜类化合物的半合成、修饰及生物活性研究进展


人参是世界上消费最广泛的草药之一，在对抗疲劳和缓解压力方面发挥着重要作用。人参的主要活性物质是人参皂甙。 Ocotillol 型三萜类化合物是越南人参中一种非常有效的人参皂苷，因其潜在的抗菌、抗癌和抗炎等特性而受到关注。近年来，奥克替醇类化合物的半合成、修饰和生物活性得到了广泛的研究。本综述的目的是总结奥克替洛尔类化合物的半合成、修饰和药理活性。报告了这些化合物的结构-活性关系研究。该总结应该为奥克替洛尔型衍生物的药物探索提供有用的信息。