Cyclodextrins (CDs) are naturally occurring cyclic oligosaccharides consisting of multiple glucose subunits. CDs are widely used in host–guest chemistry and biochemistry due to their structural advantages, biocompatibility, and ability to form inclusion complexes. Recently, CDs have become of high interest in the field of medical imaging as a potential scaffold for the development of a large variety of the contrast agents suitable for magnetic resonance imaging, ultrasound imaging, photoacoustic imaging, positron emission tomography, single photon emission computed tomography, and computed tomography. The aim of this review is to summarize and highlight the achievements in the field of cyclodextrin-based contrast agents for medical imaging.

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用于医学成像的基于环糊精的造影剂

环糊精 (CD) 是天然存在的环状寡糖，由多个葡萄糖亚基组成。由于其结构优势、生物相容性和形成包合物的能力，CD 被广泛用于主客体化学和生物化学。最近，CD 已成为医学成像领域的一种潜在支架，用于开发适用于磁共振成像、超声成像、光声成像、正电子发射断层扫描、单光子发射计算机断层扫描的各种造影剂。 ，和计算机断层扫描。本综述的目的是总结和突出基于环糊精的医学成像造影剂领域的成就。