Background Non-specific low back pain (LBP) is the leading cause of disability worldwide. The primary physiotherapeutic treatment for LBP is physical exercise, but evidence suggesting a specific exercise as most appropriate for any given case is limited. Objective To determine if specific stabilization exercise (SSE) is more effective than traditional trunk exercise (TTE) in reducing levels of pain, disability and inflammation in women with non-specific low back pain (LBP). Design A pilot randomized controlled trial was conducted in Rovira i Virgili University, Catalonia. Methods Thirty-nine females experiencing non-specific LBP were included in two groups: the TTE program and SSE program, both were conducted by a physiotherapist during twenty sessions. The primary outcome was pain intensity (10-cm Visual Analogue Scale). Secondary outcomes were disability (Roland Morris Disability Questionnaire), and inflammation (IL-6 and TNF-α plasma levels). Measurements were taken at baseline, at half intervention, at post-intervention, and a month later. Results Mean group differences in change from baseline to post-intervention for TTE were: −4.5 points (CI 3.3 to 5.6) for pain, −5.1 points (CI 3.0 to 7.3) for disability, 0.19 pg/mL (95% CI [−1.6–1.2]) for IL-6 levels, and 46.2 pg/mL (CI 13.0 to 85.3) for TNF-α levels. For SSE, differences were: −4.3 points (CI 3.1 to 5.6) for pain, −6.1 points (CI 3.7 to 8.6) for disability, 1.1 pg/mL (CI 0.0 to 2.1) for IL-6 levels , and 12.8 pg/mL (95% CI [−42.3–16.7]) for TNF-α levels. There were an insignificant effect size and no statistically significant overall mean differences between both groups. Conclusion This study suggests that both interventions (traditional trunk and specific stabilization exercises) are effective in reducing pain and disability in non-specific LBP patients, but the two programs produce different degrees of inflammation change. Clinical trial registration number NCT02103036.

中文翻译：

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与传统躯干运动相比，特定稳定运动对非特异性腰痛女性的有效性：一项试点随机对照试验

背景 非特异性腰痛 (LBP) 是全球残疾的主要原因。LBP 的主要物理治疗方法是体育锻炼，但表明特定锻炼最适合任何特定病例的证据有限。目的 确定特定稳定运动 (SSE) 在减轻非特异性腰痛 (LBP) 女性的疼痛、残疾和炎症水平方面是否比传统的躯干运动 (TTE) 更有效。设计 在加泰罗尼亚的 Rovira i Virgili 大学进行了一项初步随机对照试验。方法 39 名经历非特异性 LBP 的女性被分为两组：TTE 计划和 SSE 计划，均由物理治疗师进行 20 次治疗。主要结果是疼痛强度（10 厘米视觉模拟量表）。次要结果是残疾（罗兰莫里斯残疾问卷）和炎症（IL-6 和 TNF-α 血浆水平）。在基线、半干预、干预后和一个月后进行测量。结果 TTE 从基线到干预后变化的平均组差异为：疼痛为 -4.5 分（CI 3.3 至 5.6），残疾为 -5.1 分（CI 3.0 至 7.3），0.19 pg/mL（95% CI [- IL-6 水平为 1.6–1.2]），TNF-α 水平为 46.2 pg/mL（CI 13.0 至 85.3）。对于 SSE，差异为：疼痛为 -4.3 分（CI 3.1 至 5.6），残疾为 -6.1 分（CI 3.7 至 8.6），IL-6 水平为 1.1 pg/mL（CI 0.0 至 2.1）和 12.8 pg/ mL (95% CI [−42.3–16.7]) 用于 TNF-α 水平。两组之间的效应量不显着，总体平均差异无统计学意义。结论 本研究表明，这两种干预措施（传统的躯干和特定的稳定练习）均能有效减轻非特异性下腰痛患者的疼痛和残疾，但这两种方案会产生不同程度的炎症变化。临床试验注册号NCT02103036。