The present study investigated the effects of dietary magnesium supplementation on mineral status and intermediary metabolism of ewes during the transition period (TP). For this purpose, 19 pregnant ewes (2nd and 3rd lactation) were divided into a control group (Con, n = 9) kept on a daily magnesium intake of approximately 3.0 g ante-partum (a.p.) and 5.0 g post-partum (p.p.), and a magnesium group (Mg, n = 10, 4.2 g a.p., 7.7 g p.p.). Blood was collected at day (d) 30 a.p., d 14 a.p., d 1 p.p., d 14 p.p. and d 30 p.p., respectively. Serum levels of total magnesium were not affected by the treatment. In Con animals, serum levels of total calcium and phosphate were lower at d 1 p.p. in comparison to d 30 a.p. (P ≤ 0.05). Only in Con ewes, serum glucose levels showed significant fluctuations throughout the entire observation period (P ˂ 0.05) and were correlated negatively with those of beta-hydroxybutyrate (r²: 0.70; P < 0.01, r²: 0.76; P < 0.01) and positively with insulin (r²: 0.46; P < 0.05, r²: 0.59; P < 0.05) on d 30 and 14 a.p., respectively. At d 30 p.p., serum insulin levels were lower in the Mg group compared to the Con group (P < 0.05). As serum concentrations of calcium, phosphate and glucose seemed more stable throughout the TP, magnesium supplementation might be an approach to promote metabolic health in ewes.

本研究调查了过渡时期（TP）期间饮食中补充镁对母羊矿物质状态和中间代谢的影响。为此，将19只怀孕母羊（第2和第3泌乳期）分为对照组（对照组，n  = 9），每天摄入约3.0 g产前（ap）和5.0 g（产后（pp））的镁。 ）和一个镁基（Mg，n  = 10，4.2 g ap，7.7 g pp）。在（d）30 ap，d 14 ap，d 1 pp，d 14 pp和d 30 pp分别采血。血清总镁水平不受治疗的影响。在Con动物中，与d 30 ap相比，d 1 pp时血清总钙和磷酸盐水平较低（P ≤0.05）。只有在精读母羊，血清葡萄糖水平在整个观察期间（显示显著波动P ˂0.05）和与那些β-羟丁酸盐的负相关（r ²：0.70; P  <0.01，R ²：0.76; P  <0.01） 分别在ap 30和14 ap时胰岛素阳性（r ²：0.46；P  <0.05，r ²：0.59；P <0.05）。在第30 pp时，Mg组的血清胰岛素水平低于Con组（P <0.05）。由于整个TP中血清钙，磷酸盐和葡萄糖的浓度似乎更稳定，因此补充镁可能是促进母羊代谢健康的一种方法。