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In vitro action of leptin on gonadotropin secretion in pre-pubertal male chub mackerel
Comparative Biochemistry and Physiology A: Molecular & Integrative Physiology ( IF 2.1 ) Pub Date : 2020-11-27 , DOI: 10.1016/j.cbpa.2020.110856
Hirofumi Ohga 1 , Michiya Matsuyama 2
Affiliation  

Leptin directly influences gonadotropin (GTH) secretion from female pituitary cells in vitro and is a key signal at the onset of puberty in female chub mackerel (Scomber japonicus). Here, we investigated whether leptin also influences GTH secretion in male chub mackerel. The addition of 1 nM homologous recombinant leptin to pre-pubertal male pituitary cells stimulated follicle-stimulating hormone secretion after 1 and 2 h of culture. Therefore, leptin signaling could also directly facilitate GTH secretion in male chub mackerel.



中文翻译:

瘦素对青春期前雄性鲭鱼促性腺激素分泌的体外作用

瘦素直接影响体外雌性垂体细胞的促性腺激素 (GTH) 分泌,是雌性鲭鱼 ( Scomber japonicus )青春期开始时的关键信号。在这里,我们研究了瘦素是否也影响雄性鲭鱼的 GTH 分泌。向青春期前雄性垂体细胞添加 1 nM 同源重组瘦素可刺激培养 1 小时和 2 小时后的促卵泡激素分泌。因此,瘦素信号也可以直接促进雄性鲭鱼的 GTH 分泌。

更新日期:2020-12-11
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