Rapid urbanization and industrialization have greatly impacted the inherent soil composition. Heavy metals disposed in the environment by anthropogenic activities toxicate flora and ultimately affect the phytochemical profile of medicinal plants. We report here such an investigation of the heavy metal concentrations in the leaf extract of Solanum virginianum (S. virginianum). This work has been extended to observe the phytochemical constituents and antibacterial significance of leaf extracts in methanol and aqueous medium. The metal concentration was analysed on ICE 3000 series atomic absorption spectrometer. The antibacterial assessment was carried by disc diffusion technique against three gram-negative (Escherichia coli, Salmonella typhi, and Pseudomonas aeruginosa) and one gram-positive (Staphylococcus aureus) bacteria. The content of Iron (Fe), Manganese (Mn), Zinc (Zn), and Lead (Pb) were 2.04, 0.47, 0.41, and 0.10 mg/L, respectively. Saponin and coumarin were present in both extracts. Various other phytochemicals like steroids, terpenoid, and flavonoid, were present only in the water extract, while tannin was present only on methanol extract. The methanol and aqueous extracts exhibited their highest inhibition on S. aureus with zones of inhibition of 12 mm and 14 mm, respectively. The aqueous extract possessed more phytochemicals than the methanol extract, and the aqueous extract exhibited better antibacterial activity. The high Fe content in the leaf extract may suggest its use as an anaemic medicine. Other metal contents are under the WHO range.

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茄子叶提取物中重金属含量与生物学意义的相关性研究

快速的城市化和工业化极大地影响了土壤的固有成分。通过人为活动而沉积在环境中的重金属会使植物群中毒，并最终影响药用植物的植物化学特征。我们在这里报告了对茄子（S. virginianum）叶片提取物中重金属浓度的调查。这项工作已扩展到观察甲醇和水介质中叶提取物的植物化学成分和抗菌意义。在ICE 3000系列原子吸收光谱仪上分析金属浓度。通过圆盘扩散技术对三种革兰氏阴性（大肠杆菌，伤寒沙门氏菌和铜绿假单胞菌）和一种革兰氏阳性（金黄色葡萄球菌）细菌进行抗菌评估。铁（Fe）的含量 锰（Mn），锌（Zn）和铅（Pb）分别为2.04、0.47、0.41和0.10 mg / L。两种提取物中均存在皂苷和香豆素。水提取物中仅存在类固醇，萜类和黄酮类化合物等其他植物化学物质，而甲醇提取物中仅存在丹宁酸。甲醇和水提取物对金黄色葡萄球菌的抑制作用最高，分别为12 mm和14 mm。水提取物比甲醇提取物具有更多的植物化学物质，并且水提取物表现出更好的抗菌活性。叶提取物中的高铁含量可能表明其可用作贫血药。其他金属含量在WHO范围内。两种提取物中均存在皂苷和香豆素。水提取物中仅存在类固醇，萜类和黄酮类化合物等其他植物化学物质，而甲醇提取物中仅存在丹宁酸。甲醇和水提取物对金黄色葡萄球菌的抑制作用最高，分别为12 mm和14 mm。水提取物比甲醇提取物具有更多的植物化学物质，并且水提取物表现出更好的抗菌活性。叶提取物中的高铁含量可能表明其可用作贫血药。其他金属含量在WHO范围内。两种提取物中均存在皂苷和香豆素。水提取物中仅存在类固醇，萜类和黄酮类化合物等其他植物化学物质，而甲醇提取物中仅存在丹宁酸。甲醇和水提取物对金黄色葡萄球菌的抑制作用最高，分别为12 mm和14 mm。水提取物比甲醇提取物具有更多的植物化学物质，并且水提取物表现出更好的抗菌活性。叶提取物中的高铁含量可能表明其可用作贫血药。其他金属含量在WHO范围内。甲醇和水提取物对金黄色葡萄球菌的抑制作用最高，分别为12 mm和14 mm。水提取物比甲醇提取物具有更多的植物化学物质，并且水提取物表现出更好的抗菌活性。叶提取物中的高铁含量可能表明其可用作贫血药。其他金属含量在WHO范围内。甲醇和水提取物对金黄色葡萄球菌的抑制作用最高，分别为12 mm和14 mm。水提取物比甲醇提取物具有更多的植物化学物质，并且水提取物表现出更好的抗菌活性。叶提取物中的高铁含量可能表明其可用作贫血药。其他金属含量在WHO范围内。