Phenolic compounds (quercetin, rutin, cyanidin, tangeretin, hesperetin, curcumin, resveratrol, etc.) are known to have health-promoting effects and they are accepted as one of the main proposed nutraceutical group. However, their application is limited owing to the problems related with their stability and water solubility as well as their low bioaccessibility and bioavailability. These limitations can be overcome by encapsulating phenolic compounds by physical, physicochemical and chemical encapsulation techniques. This review focuses on the effects of encapsulation, especially lipid-based techniques (emulsion/nanoemulsion, solid lipid nanoparticles, liposomes/nanoliposomes, etc.), on the digestibility characteristics of phenolic compounds in terms of bioaccessibility and bioavailability.

中文翻译：

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脂质封装对酚类化合物生物可及性和生物利用度的影响


已知酚类化合物（槲皮素、芦丁、矢车菊素、橘子素、橙皮素、姜黄素、白藜芦醇等）具有促进健康的作用，并且它们被认为是主要的营养保健品组之一。然而，由于其稳定性和水溶性以及生物可及性和生物利用度低等问题，它们的应用受到限制。这些限制可以通过物理、物理化学和化学封装技术封装酚类化合物来克服。本综述重点关注封装，特别是基于脂质的技术（乳液/纳米乳液、固体脂质纳米粒子、脂质体/纳米脂质体等）对酚类化合物消化特性（在生物可及性和生物利用度方面）的影响。